An image of a woman playing basketball.

An image of a woman playing basketball.

#2 Vanderbilt vs. #6 Notre Dame Prediction, Odds, & How to Watch: March Madness® 2026

#2 Vanderbilt and #6 Notre Dame meet at Dickies Arena in Fort Worth for a high-stakes Sweet 16® matchup. Here are details, our prediction, and how to watch with Sling TV.

Get ready for a clash of styles in a Lone Star State March Madness® showdown! The #2 Vanderbilt Commodores are back in the Sweet 16® for the first time in 17 years, and they are doing it with some serious flair. Standing in their way is a #6 Notre Dame Fighting Irish squad that is shooting the lights out at the perfect time, having won nine of their last ten games.

While the Dores have been nearly invincible this season, the Irish bring a tournament pedigree that is hard to ignore. This isn't just a game; it's a battle for a spot in the Elite Eight, and both teams are ready to leave it all on the hardwood.

To watch the Commodores vs. Fighting Irish Sweet 16 game with Sling, use the link below for a 1 Day Pass subscription with ESPN.

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Game Detail
Information
Matchup
#2 Vanderbilt vs. #6 Notre Dame
Date / Time
Friday, March 27, 2026
Location
Dickies Arena, Fort Worth, TX
Channel
ESPN
Watch With Sling
1, 3, & 7 Day Pass or a monthly subscription to Sling Orange
Opening Spread
Vanderbilt -5.5 (O/U 151.5)

Vanderbilt Commodores Analysis

https://youtu.be/ZvkvheS0ZQk?si=gH72mGjzHlQ6lUGi

Season Overview: Shea Ralph has led Vanderbilt (29-4) to a historic season, finishing second in a brutal SEC. The Dores have been an offensive juggernaut, ranking 8th nationally in scoring (84.9 PPG) and 6th in offensive efficiency.

Notre Dame Fighting Irish Analysis

Season Overview: Under Niele Ivey, the Irish (24-10) have overcome early-season hurdles to become one of the most dangerous #6 seeds in recent memory. They lean on a defense that forces nearly 20 turnovers per game, turning mistakes into easy transition points.

Key Matchup & Advanced Analytics

Final Prediction & Betting Pick

The Verdict: Vanderbilt Commodores

Final Score Prediction: Vanderbilt 78, Notre Dame 74

Best Bet: Notre Dame +5.5

Frequently Asked Questions

Who is the favorite in Vanderbilt vs. Notre Dame? Vanderbilt is currently a 4.5-point favorite.

Where can I stream the 2026 NCAA Tournament? You can stream the Women’s Tournament by subscribing to Sling Orange + Blue with ESPN and, in designated markets, ABC.

What time is the Vanderbilt game? Tip-off is at 2:30 PM ET on Friday, March 27, airing on ESPN.

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